SSRI Litigation

Celexa and Suicide

One surprising fact about suicide is that antidepressant use, which is supposed to improve one’s mood, can be one of the causes of suicide.

Celexa is an antidepressant which is a selective serotonin reuptake inhibitor (SSRI). Doctors prescribe it for major depression. Celexa has been linked to suicidal behavior in multiple clinical trials.1 2 The medication may also contribute to teenage suicide.

Clinical trials

John McManamy, an author who has bipolar disorder, has researched the extensive list of clinical trials showing that SSRIs can lead to suicidal behavior. For Celexa, he found that:1

  • One study found no problems with the drug.
  • A second study found a “possibly suicide-related” risk rate of 13 percent each (compared to a suicide risk of 8 percent with a placebo*).
  • A third study found the drug superior to the placebo.
  • A fourth study found that the risk of suicidality or self-harm was 11.6 percent (compared to a rate of 4.5 percent with a placebo*), but that suicidal thinking was lower with the drug than with the placebo.

Food and Drug Adminstration and the United Kingdom’s Medicine and Healthcare Products Regulatory Agency conducted the studies.

*A placebo is a pill, medicine, or procedure which is harmless and has no medical effect.

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